Source-backed longevity intelligence

Bryan Johnson knowledge base.

A concise, curated briefing on Bryan Johnson, Blueprint, Don't Die, and measurement-first longevity ideas — synthesized from the local llm-wiki into public, reader-friendly context.

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Protocol

Kate Tolo launches female-specific Blueprint measurement protocol

Johnson announced that Kate Tolo will spend about $2M/year and three months establishing a cycle-aware baseline for a female-specific longevity protocol, with data and learnings promised publicly.

Female Blueprint 3 sources
Product

Blueprint biomarker platform: 100+ biomarkers, AI action plan, retesting

Blueprint positions testing as a consumer product: 100+ biomarkers, 160+ yearly measurements, imported past labs, AI-generated evidence-backed action plans, and six-month retesting.

Biomarkers 1 source
Testing

Microplastics become a Blueprint testing/product theme

Johnson claimed an N=1 semen microplastics reduction and tied it to sauna, reverse-osmosis water, and plastic avoidance; Blueprint also offers a $135 at-home blood microplastics test. Treat causality cautiously.

Microplastics 2 sources
Marketplace

Blueprint starts certifying partner products

Johnson said Blueprint launched a certified-brand marketplace, initially naming Eight Sleep and Plunge Sauna, with products vetted by his clinical team and studied for longevity.

Certified partners 1 source
Positioning

Blueprint/Don't Die positioning

Johnson said he nearly shut down Blueprint to focus on Don't Die, then recast Blueprint as the practical company layer aligned with the ideology.

Don't Die infrastructure 1 source

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Core topics

entity medium updated 2026-05-22

Blueprint

Blueprint is bryan-johnson's longevity protocol, product company, and public measurement system. It began as Project Blueprint, an N=1 effort to measure Johnson's organs and biological aging, and later became a consumer

#product#company#longevity#health#biomarkers
concept medium updated 2026-05-22

Blueprint Protocol

The Blueprint Protocol is bryan-johnson's closed-loop health system: measure body state, consult scientific evidence, implement interventions, measure again, and update. Johnson treats the body as a system whose organs a

#protocol#longevity#health#biomarkers#biohacking
concept medium updated 2026-05-22

Don't Die

Don't Die is bryan-johnson's community slogan, longevity philosophy, and civilizational frame. The official Don't Die page describes a community “united in defeating all causes of human and planetary death and building a

#longevity#biohacking#health#protocol#open-question
concept medium updated 2026-05-22

Biomarker-driven longevity protocols

A biomarker-driven longevity protocol is a health system that treats the body as a measurable control system: collect biomarkers, choose interventions, re-measure, and iterate. project-blueprint is the most visible curre

#longevity#biomarkers#health#biohacking#protocol

Recently updated material

Changelog

  1. Recent news/changelog curation pass

    Separated high-signal recent overview items from chronological wiki/site/content updates.

    queries/bryan-johnson-recent-news-changelog.md

  2. Blueprint Biomarkers page captured

    Captured the product page describing 100+ biomarkers, 160+ yearly measurements, AI health companion/action plan, imported past labs, and twice-yearly testing.

    raw/articles/bryan-johnson/blueprint-biomarkers-2026-05-22.md

  3. Bryan Johnson, Blueprint, Don't Die, and @bryan_johnson

    Captured first-party raw sources from bryanjohnson.com, dontdie.bryanjohnson.com, Blueprint pages, and X/Twitter @bryanjohnson into raw/articles/ with sha256 frontmatter.

    concepts/algorithmic-health.mdconcepts/biomarker-driven-longevity-protocols.mdentities/blueprint.mdconcepts/blueprint-protocol.mdentities/braintree.md +7 more

  4. Bryan Johnson / Blueprint / Don't Die research

    Researched official Bryan Johnson site, Blueprint, Don't Die, recent @bryanjohnson X/Twitter posts, TIME, Chicago Booth, WIRED/Blueprint, and People/Netflix profile coverage.

    concepts/algorithmic-health.mdconcepts/biomarker-driven-longevity-protocols.mdentities/blueprint.mdconcepts/blueprint-protocol.mdentities/braintree.md +7 more

  5. Bryan Johnson index/source-map cleanup

    Added queries/bryan-johnson-source-map.md to index.md and corrected its archived project-blueprint links to canonical blueprint-protocol.

    concepts/algorithmic-health.mdconcepts/biomarker-driven-longevity-protocols.mdentities/blueprint.mdconcepts/blueprint-protocol.mdentities/braintree.md +7 more

  6. Bryan Johnson wiki reconciliation

    Reconciled duplicate pages after discovering existing Bryan Johnson pages outside the stale index.

    concepts/algorithmic-health.mdconcepts/biomarker-driven-longevity-protocols.mdentities/blueprint.mdconcepts/blueprint-protocol.mdentities/braintree.md +7 more

  7. Years critique of biomarker limits

    Third-party coverage argues Johnson's biomarker volume raises useful preventive-health awareness while retaining N=1, surrogate-endpoint, confounding, and clinical-interpretation lim…

    raw/articles/bryan-johnson/years-biomarkers-limits-2026-04-20.md

  8. Bryan Johnson's Protocol page / Don't Die protocol refresh

    Protocol content foregrounds Don't Die, health-as-game framing, resting heart rate before bed, sleep, exercise, nutrition, oral care, skin/hair, clean water, and measurement.

    raw/articles/blueprint-bryan-johnsons-protocol-2026-01-23.mdraw/articles/bryan-johnson/bryan-johnson-protocol-2026-05-22.md

  9. TIME profile: free longevity tip and mainstream critique

    TIME summarizes Johnson's Don't Die philosophy, Blueprint product/funding context, and criticism from longevity scientists.

    raw/articles/time-bryan-johnson-longevity-2026.md