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last curated pass Jul 23, 2026 · 8 public entries · source-aware summaries from 6 legacy curated cards plus llm-wiki tweets

Recent curated signals

Protocol update Johnson turns his sauna experiment into a public checklist Johnson recommended 4–7 dry-sauna sessions per week, named time/temperature and core-temperature targets, and added hydration, fertility, air-quality, and material cautions. A separate post reported that moving his final meal from noon to 2 p.m. raised his sleep heart rate from 42 to 44 bpm. The dashboard treats both as Johnson’s attributed N=1 protocol positioning—not a reader prescription or independent evidence of longevity benefit. Rx catalog Immortals Rx names six GLP-1 options for weight loss and longevity Johnson said Immortals Rx now lists six GLP-1 options: Zepbound, Wegovy injections and tablets, Foundayo tablets, compounded tirzepatide, and compounded semaglutide. He connected the catalog to weight loss, food-noise management, and possible longevity relevance after a time-zone shift. The post cites no named studies and is not evidence that any option is safe or effective for longevity; formulation, compounded-treatment, prescribing, and availability details were not independently verified by this curation. Frontier biotech Johnson frames autologous iPSCs as a personal disease-resolution platform Johnson called a dish-grown, reprogrammed cell model a newborn “clone” of himself and proposed therapy testing, organ growth, cell transplantation, and disease repair. He says blood-derived cells exposed to Yamanaka factors became pluripotent and pointed generally to related clinical-trial work, but supplied no cell-line characterization, trial citations, organ, therapy, safety, or outcome data. The dashboard treats this as attributed biotech and immortality positioning—not evidence of a human clone or a clinically available personalized-organ platform. Measurement Eye-health agenda advances to a 15-marker tear-panel plan Johnson reported using paper strips to collect tears for a $1,800 specialty-lab panel spanning 15 inflammatory, tissue-degradation, and regenerative-signaling biomarkers. He says the panel will establish an ocular-surface baseline and track a forthcoming eye protocol. No results, diagnosis, intervention, reference range, clinical-utility evidence, or outcome was published, so this remains an N=1 measurement plan—not an eye-health protocol or medical advice. Strategy Johnson says his project shifted toward disease resolution and frontier biotech Johnson said an unspecified “incurable disease” diagnosis shifted his project “overnight” from longevity staples toward disease resolution and frontier biotech. In a same-day thread, he also identified eye health as a possible longevity gap and called for robust measurement, dysfunction diagnosis, and corrective protocols rather than only diet or supplements. The dashboard treats this as a strategic and measurement-agenda signal: the disease, research targets, tests, therapies, and outcomes were not named, independently validated, or offered as medical advice. Research watch Johnson flags ex vivo work on reversing age-related protein crosslinks Johnson amplified an unnamed laboratory result that he says used AlphaFold to search 45,000 oxidases and directed evolution to screen more than 500 million engineered variants against age-related sugar–protein crosslinking. He also stated that the work remains ex vivo and that safe delivery of a large bacterial enzyme into living tissue is unresolved. The dashboard treats this as a low-confidence research lead—not a demonstrated human treatment, independently validated result, protocol change, or medical advice. Female health Kate Tolo’s 90-day program scales to 1,900 claimed biomarkers Johnson announced a 90-day Kate Tolo program spanning three menstrual cycles, 50+ devices, 100 daily tasks, and a projected 1,900 biomarkers / 14.8 million data points. He framed it as making cyclical female biology “legible.” The dashboard treats those numbers as Johnson’s planned program specification—not a completed dataset, independently validated study, general protocol, or medical advice. Algorithmic health Resting heart rate becomes Johnson’s “Sovereignty Index” Johnson recast pre-sleep resting heart rate as a score for whether impulses and engineered consumption are controlling him, reporting a personal 41 bpm 30-day average and prescribing evening pre-commitments around food, screens, caffeine, light, bedtime, and winding down. The named proxy is a useful algorithmic-health frame, but 41 bpm is his self-report—not a reader target, diagnosis, or medical advice.

// Reference paths

Move from feed to dossiers

Each route keeps source trails and medical caution visible.
Protocol Health

Habits, Longterm, and Don’ts for measurement loops, sleep consistency, oral care, exercise, and experimental-intervention caution.

Protocol Longevity

Habits, Longterm, and Don’ts for biomarkers, healthspan basics, critiques, and low-confidence immortality claims.

Protocol Nutrition

Habits, Longterm, and Don’ts for plant-led meals, Blueprint products, microplastics claims, and metabolic-drug caveats.

Protocol Sleep

Habits, Longterm, and Don’ts for bedtime discipline, front-loading examples, and metric caution from tweet-backed sources.

Reference Concepts

35 source-aware glossary entries, including concepts without dedicated wiki pages yet.

entity Blueprint

Blueprint is bryan-johnson's longevity protocol, product company, and public measurement system. It began as Project Blueprint, an N=1 effort to measure Johnson's organs and biological aging, and later became a consumer

concept Blueprint Protocol

The Blueprint Protocol is bryan-johnson's closed-loop health system: measure body state, consult scientific evidence, implement interventions, measure again, and update. Johnson treats the body as a system whose organs a

concept Don't Die

Don't Die is bryan-johnson's community slogan, longevity philosophy, and civilizational frame. The official Don't Die page describes a community “united in defeating all causes of human and planetary death and building a

concept Biomarker-driven longevity protocols

A biomarker-driven longevity protocol is a health system that treats the body as a measurable control system: collect biomarkers, choose interventions, re-measure, and iterate. project-blueprint is the most visible curre

Signal Metrics

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