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// REFERENCE / concepts

Concepts

A 27-entry glossary for Blueprint, Don't Die, biomarker protocols, Female-specific Blueprint, source-aware critiques, and tweet-backed concepts that do not yet have dedicated wiki pages.

Source-aware summaries only; not medical advice. Confidence labels describe public-dashboard certainty, not clinical truth.

#01medium

Kate Tolo endometriosis diagnostic triangulation

Johnson says an endo-specific ultrasound, AI-assisted pelvic MRI, and microRNA/protein blood test converged on a non-surgical endometriosis diagnosis; useful as a multi-modality measurement case study, not medical advice or cure evidence.

raw/articles/bryan-johnson/x-twitter-daily-2026-07-10.md
#02medium

AIG cure roadmap / Bryan in a dish

Johnson proposed a staged AIG cure attempt using live T-cell matching, biweekly blood/wearable monitoring, cryopreserved immune cells, and ex-vivo therapy tests; roadmap evidence, not an approved cure.

raw/articles/bryan-johnson/x-twitter-daily-2026-07-09.md
#03medium

AIG low ferritin / false-negative follow-up

Johnson recast his AIG story as an 11-year low-ferritin diagnostic miss and reported Monoferric ferritin follow-up; useful as measurement ethos, not iron-treatment advice.

raw/articles/bryan-johnson/x-twitter-daily-2026-07-08.md
#04medium

AIG single-cell immune-receptor sequencing

Johnson says he is sequencing 1M immune cells to identify autoreactive clones behind autoimmune gastritis; a cellular/receptor-level measurement layer, not a proven therapy or reader recommendation.

raw/articles/bryan-johnson/x-twitter-daily-2026-07-04.md
#05medium

Inherited-cancer DNA + RNA risk panel

Johnson reported a negative 71-gene Invitae inherited-cancer panel with DNA plus RNA analysis; useful as a risk-stratification measurement signal, not clinical screening advice.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-26.md
#06low

Immortality manifesto / Die Economy

Johnson’s June 24 essay defines immortality as life expectancy gains outpacing aging and introduces the Die Economy vs Don’t Die Economy frame; important ideology, not validation of the 2039 forecast.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-25.md
#07medium

Wearable relative tracking

Johnson argues divergent wearable numbers can still be useful for within-device trend tracking; this supports longitudinal measurement while leaving accuracy questions open.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-25.md
#08medium

Midjourney scanner / structural imaging layer

Johnson’s June 23 essay frames blood draws, wearables, and imaging as chemical/functional/structural measurement layers; useful methodology signal, not proof the device improves outcomes.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-24.md
#09medium

Quarterly international travel cap

Johnson suggests at most one international trip per quarter based on his travel biomarker recovery; N=1 behavioral prescription, not clinical guidance.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-24.md
#10medium

Immortals Rx GLP-1 / peptide expansion

Johnson announced semaglutide/Wegovy, tirzepatide/Zepbound, SGLT2 inhibitors, peptide complexes, glutathione, and NAD+ as part of a wider Immortals Rx catalog; commercial platform news, not medication advice.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-23.md
#11medium

Immortals company rename

Johnson explicitly says the company has changed its name to Immortals; notable as movement/brand positioning, not a medical claim.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-20.md
#12medium

Australian sun skin-aging readout

A June 2026 N=1 skin-aging metric claim after Australia travel; useful as protocol readout context, not independent validation.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-20.md
#13medium

Blueprint Protocol

The measurement-led routine and intervention stack Johnson presents as Blueprint.

concepts/blueprint-protocol.md
#14medium

Akkermansia + butyrate Blueprint product

A June 2026 microbiome supplement launch; notable as product expansion, not clinical validation.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-19.md
#15medium

Jet lag caffeine + melatonin follow-up

Johnson’s N=1 circadian recovery claim using glucose as readout after Australia travel.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-19.md
#16medium

Biomarker-driven longevity protocols

The feedback-loop idea that biomarkers guide protocol changes, with caveats about outcomes.

concepts/biomarker-driven-longevity-protocols.md
#17medium

Sauna heat-dose / HSP27 self-experiment

A June 2026 N=1 test using ingestible temperature tracking and blood biomarkers; useful as protocol design, not medical advice.

raw/articles/bryan-johnson/x-twitter-daily-2026-06-17.md
#18medium

Algorithmic Health

Delegating health decisions to measurement, rules, and repeatable systems.

concepts/algorithmic-health.md
#19medium

Don't Die

Johnson’s anti-death ideology and movement framing.

concepts/dont-die.md
#20low

Immortality by 2039

An aspirational longevity claim that should stay clearly low-confidence.

concepts/immortality-by-2039.md
#21medium

Project Blueprint

The company/protocol ecosystem around Johnson’s routine, products, and measurement claims.

entities/project-blueprint.md
#22medium

Blueprint

The public brand/entity layer for products, protocol content, and community positioning.

entities/blueprint.md
#23medium

Female-specific Blueprint / Kate Tolo protocol

A cycle-aware baseline project; source-aware because no dedicated synthesized wiki page exists yet.

queries/bryan-johnson-recent-news-changelog.md + raw X/Kate articles
#24medium

Enhanced Games / measured human enhancement

Johnson’s enhancement-competition framing, not independent safety validation.

raw/articles/bryan-johnson/x-twitter-daily-2026-05-25.md
#25medium

Protocol reversibility / intervention reversal

The principle that a protocol can reverse or pause interventions when measurements or risk assessments change.

raw/articles/bryan-johnson-x-paused-metformin-2025-08-07.md
#26medium

Biomarkers vs clinical outcomes

The critique that biomarker improvements do not automatically prove better long-term outcomes.

raw/articles/bryan-johnson/years-biomarkers-limits-2026-04-20.md
#27low

Don't Die as AI alignment / anti-entropy

The broader ideology tying health, survival, AI-era alignment, and anti-entropic framing together.

raw/articles/bryan-johnson-x-targeted-searches-2026-05-22.md